Stuart Millheiser: Do Genetics Play Into ALS?

By Jason McDonald


When it comes to the causes of ALS, Stuart Millheiser can tell you that there is little in the way of solid information. Simply put, we do not know what causes this condition to arise, and it seems like there is no one who is at more risk than someone else. This is one of the reasons why research is done, and it seems like new information has come about in relation to this topic. Specifically, I would like to talk about the potential of genetics, as it relates to this condition.

As an article on Genetic Literacy Project detailed, around 90 percent of ALS cases are unknown, as far as their origins are concerned. With that said, there has been speculation that the other 10 percent or so may have some sort of connection genetics. To push this idea along, a study in the American Journal of Human Genetics covered C9orf72, which is a type of gene that may have some kind of influence on ALS. Mutations were observed in five offspring. What's interesting is that while four out of those five cases were diagnosed with this condition, their parents and grandparents were not.

I am sure that Stuart Millheiser and others can attest to the intrigue associated with the study. The article also mentioned that C9orf72 is routinely observed in healthy neurons, within the nuclear membrane to be more precise. However, when it comes to diseased neurons, the aforementioned gene is seen in the plasma membrane. This plays negatively into the idea of protein, which is needed in order to keep muscular functions at a high level.

I believe that, more than anything else, these details illustrate the numerous values often associated with ALS. For those who are curious to know how they can help individuals with this condition, as well as push awareness to a higher level, Stuart Millheiser can draw your attention to numerous options. You may be able to grant donations, the proceeds of which will go to research. With this form of financial backing, it's easy to see that specialists can uncover even more information.

To say that this information is useful would be an understatement, especially when you consider that there isn't much in the way of solid information regarding ALS. It's easy to see that activists are constantly seeking new details, as they relate to causes, cures, and the like. Because of studies like the one discussed here, though, the activists in question should rest easier. Science is powerful, and the aforementioned information illustrates why this is.




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